{"id":245667,"date":"2023-09-06T19:41:31","date_gmt":"2023-09-06T19:41:31","guid":{"rendered":"https:\/\/www.echitabplusicp.org\/echitab-plus-icp"},"modified":"2023-09-07T13:07:08","modified_gmt":"2023-09-07T13:07:08","slug":"echitab-plus-icp","status":"publish","type":"page","link":"https:\/\/www.echitabplusicp.org\/pt-pt\/echitab-plus-icp","title":{"rendered":"EchiTAb-Plus-ICP"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text admin_label=”Product” _builder_version=”4.16″ _module_preset=”73bb68af-13e3-4cf6-96fe-2f175413a0a5″ header_font=”Montserrat|500|||||||” header_font_size=”55px” header_2_font_size=”35px” header_2_line_height=”1.3em” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

EchiTAb-Plus-ICP<\/h1>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_3,1_3,1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_3″ admin_label=”Coluna” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_image src=”https:\/\/www.echitabplusicp.org\/wp-content\/uploads\/2022\/03\/ucr.png” title_text=”ucr” admin_label=”UCR” _builder_version=”4.16″ _module_preset=”default” width=”30%” module_alignment=”right” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_image][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text admin_label=”Instituto” _builder_version=”4.16″ _module_preset=”_initial” text_font=”Times New Roman|600||on|||||” header_font=”Times New Roman|600|||||||” header_text_color=”#3D3D3D” header_line_height=”1.8em” header_2_font=”Times New Roman|||on|||||” header_2_text_color=”#3D3D3D” header_2_line_height=”1.3em” header_3_font=”Times New Roman||||||||” header_3_text_color=”#3D3D3D” header_3_line_height=”1.3em” custom_padding=”||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

INSTITUTO
CLODOMIRO PICADO<\/strong>
Univerdad da Costa Rica<\/strong>
<\/span><\/span><\/h3>\n

[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_image src=”https:\/\/www.echitabplusicp.org\/wp-content\/uploads\/2022\/03\/icp.png” title_text=”icp” admin_label=”ICP” _builder_version=”4.16″ _module_preset=”default” width=”18%” module_alignment=”left” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=”EchiTAb” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text admin_label=”EchiTAb” _builder_version=”4.16″ _module_preset=”default” text_font=”Times New Roman||||||||” text_font_size=”30px” header_font_size=”29px” header_line_height=”0.6em” header_2_font=”Times New Roman|600||||on|||” header_2_font_size=”41px” custom_margin=”2px||2px||true|false” custom_padding=”2px||2px||true|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

EchiTAb-Plus-ICP<\/h2>\n

[\/et_pb_text][et_pb_text admin_label=”Poly” _builder_version=”4.16″ _module_preset=”default” text_font=”Montserrat||||||||” text_text_color=”#3D3D3D” text_line_height=”1em” header_font=”Montserrat|500|||||||” header_line_height=”0.9em” header_4_font=”Montserrat|600||on|||||” header_4_text_color=”#3D3D3D” header_4_line_height=”1.4em” custom_margin=”0px||0px||true|false” custom_padding=”0px||0px||true|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

L\u00cdQUIDO ANTIVEN\u00cdFICO POLISPEC\u00cdFICO
(Anti-v\u00edboras, anti-elaps)<\/h4>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row admin_label=”Descri\u00e7\u00e3o” _builder_version=”4.16″ _module_preset=”default” custom_margin=”30px||2px||false|false” custom_padding=”||2px||false|false” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ admin_label=”Coluna” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text admin_label=”Description” _builder_version=”4.16″ _module_preset=”d40d3645-9756-4af1-9bbd-2e08b25b7e23″ header_text_color=”#3D3D3D” header_2_font=”Montserrat||||||||” header_2_font_size=”35px” header_2_line_height=”1.3em” header_3_font=”|600||on|||||” header_3_line_height=”0.7em” header_4_font=”Montserrat|600||on|||||” header_4_text_color=”#3D3D3D” header_5_font=”Montserrat|||on|||||” header_5_text_color=”#3D3D3D” header_5_font_size=”15px” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||true|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Descri\u00e7\u00e3o e instru\u00e7\u00f5es<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ admin_label=”Linha” _builder_version=”4.17.4″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_2″ admin_label=”Coluna” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text admin_label=”Potency” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Pot\u00eancia<\/span><\/span><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”_Each” _builder_version=”4.16″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Cada<\/span>frasco de 10 mL neutraliza pelo menos 30 mg. de veneno de E. ocellatus<\/em>, 20 mg de B. <\/span>arietans<\/em> e 2 mg de veneno de N. nigricollis<\/em><\/span>.Excipientes q.s. 10ml.<\/span><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Composition” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 4%|#ffffff 100%” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Composi\u00e7\u00e3o<\/p>\n

[\/et_pb_text][et_pb_text admin_label=”_Equine” _builder_version=”4.16″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

<\/span>Imunoglobulinas equinas q.s. de modo que cada mililitro neutralize pelo menos 3,0 mg de veneno de Echis ocellatus<\/em>, 2,0 mg de veneno de Bitis arietans<\/em> e 0,2 mg de veneno de Naja nigricollis<\/em>.<\/span><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Indications” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f4f4f4 4%|#ffffff 100%” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Indica\u00e7\u00f5es<\/p>\n

[\/et_pb_text][et_pb_text admin_label=”_Effective” _builder_version=”4.16″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Eficaz em envenenamentos induzidos por viper\u00eddeos africanos e algumas serpentes elap\u00eddicas.<\/span><\/span><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Presentation and Storage” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 4%|#ffffff 99%” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Apresenta\u00e7\u00e3o e armazenamento<\/p>\n

[\/et_pb_text][et_pb_text admin_label=”_This ” _builder_version=”4.16″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Este soro antiof\u00eddico \u00e9 distribu\u00eddo em sua forma l\u00edquida em frascos de 10 mL. Este produto deve ser armazenado sob refrigera\u00e7\u00e3o (2-8\u00b0C) e deve ser utilizado imediatamente ap\u00f3s a abertura.<\/span><\/span><\/span><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Statibility” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 4%|#ffffff 100%” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Estabilidade<\/p>\n

[\/et_pb_text][et_pb_text admin_label=”_The expiration” _builder_version=”4.17.4″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

O prazo de validade deste produto ap\u00f3s sua fabrica\u00e7\u00e3o \u00e9 de tr\u00eas anos o que \u00e9 importante verificar; tamb\u00e9m \u00e9 recomendada uma inspe\u00e7\u00e3o visual do produto. Caso observe turbidez excessiva na solu\u00e7\u00e3o ou se o produto estiver vencido, deve ser descartado.<\/p>\n

[\/et_pb_text][et_pb_text disabled_on=”off|off|off” admin_label=”Neutralizing” _builder_version=”4.19.1″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 5%|#ffffff 100%” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Espectro neutralizante de acordo com estudos cl\u00ednicos e pr\u00e9-cl\u00ednicos<\/p>\n

[\/et_pb_text][et_pb_text disabled_on=”on|on|on” admin_label=”Neutralizing” _builder_version=”4.19.1″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 5%|#ffffff 100%” background_color_gradient_start_position=”4%” disabled=”on” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Espectro neutralizante de acordo com estudos cl\u00ednicos e pr\u00e9-cl\u00ednicos<\/p>\n

[\/et_pb_text][et_pb_text disabled_on=”off|off|off” admin_label=”_Preclinical” _builder_version=”4.19.1″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Ensaios pr\u00e9-cl\u00ednicos e cl\u00ednicos realizados pelo Instituto Clodomiro Picado demonstraram que ECHITAB PLUS-ICP, PAN-AFRICAN SNAKE ANTIVENOM \u00e9 eficaz na neutraliza\u00e7\u00e3o do veneno das seguintes esp\u00e9cies de serpentes de diferentes pa\u00edses:<\/p>\n

Esp\u00e9cies de cobras<\/strong>:<\/p>\n

Bitis arietans \/ Bitis gabonica \/ Bitis rhinoceros \/ Bitis nasicornis<\/em><\/p>\n

Echis ocellatus \/ Echis leucogaster \/ Echis pyramidum<\/em><\/p>\n

Naja nigricollis \/ Naja ashei \/ Naja katiensis \/ Naja mossambica \/ Naja pallida<\/em><\/p>\n

[\/et_pb_text][et_pb_text disabled_on=”on|on|on” admin_label=”_Preclinical” _builder_version=”4.19.1″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ text_text_color=”#3D3D3D” use_background_color_gradient=”on” background_color_gradient_direction=”108deg” background_color_gradient_stops=”rgba(255,255,255,0) 4%|rgba(255,255,255,0) 100%” background_color_gradient_start=”rgba(255,255,255,0)” background_color_gradient_start_position=”4%” background_color_gradient_end=”rgba(255,255,255,0)” disabled=”on” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

Ensaios pr\u00e9-cl\u00ednicos e cl\u00ednicos realizados pelo Instituto Clodomiro Picado demonstraram que ECHITAB PLUS-ICP, PAN-AFRICAN SNAKE ANTIVENOM \u00e9 eficaz na neutraliza\u00e7\u00e3o do veneno das seguintes esp\u00e9cies de serpentes de diferentes pa\u00edses:<\/p>\n

Esp\u00e9cies de cobras<\/strong>:<\/p>\n

Bitis arietans \/ Bitis gabonica \/ Bitis rhinoceros \/ Bitis nasicornis<\/em><\/p>\n

Echis ocellatus \/ Echis leucogaster \/ Echis pyramidum \/ Echis coloratus<\/em><\/p>\n

Naja nigricollis \/ Naja ashei \/ Naja annulifera \/ Naja katiensis \/ Naja melanoleuca \/ Naja mossambica \/ Naja nigricincta \/ Naja nivea \/ Naja anchietae \/ Naja pallida<\/em><\/p>\n

Dendroaspis polylepis \/ Dendroaspis angusticeps \/ Dendroaspis jamesoni \/ Dendroaspis viridis<\/em><\/p>\n

<\/em><\/p>\n

Hemachatus haemachatus<\/em><\/p>\n

[\/et_pb_text][et_pb_text admin_label=”List” _builder_version=”4.16″ _module_preset=”2d83f41d-a2fc-49a5-9e22-591a14d0651c” custom_margin=”|||0px|false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    \n
  1. O paciente deve ser colocado em uma posi\u00e7\u00e3o confort\u00e1vel e deve ser tranquilizado.<\/span><\/li>\n
  2. N\u00e3o aplique torniquetes.<\/span><\/li>\n
  3. N\u00e3o fa\u00e7a nenhuma incis\u00e3o.<\/span><\/li>\n
  4. A administra\u00e7\u00e3o de soro antiof\u00eddico em condi\u00e7\u00f5es de campo envolve v\u00e1rios riscos, principalmente a possibilidade de rea\u00e7\u00e3o adversa \u00e0s imunoglobulinas equinas. Portanto, a administra\u00e7\u00e3o de soro antiof\u00eddico em campo deve ser considerada apenas quando houver evid\u00eancia clara de envenenamento (dor, edema, dano tecidual no local da inje\u00e7\u00e3o do veneno ou sangramento sist\u00eamico) e quando o centro de sa\u00fade mais pr\u00f3ximo estiver a mais de 6 horas longe.<\/span><\/li>\n
  5. Antes de administrar o antiveneno, \u00e9 muito importante garantir que o paciente n\u00e3o seja al\u00e9rgico a imunoglobulinas de cavalo. Isso \u00e9 feito revisando o hist\u00f3rico de alergia do paciente em geral e da administra\u00e7\u00e3o anterior de soros derivados de equinos. Al\u00e9m disso, quando o soro for administrado em campo, \u00e9 necess\u00e1rio realizar um teste de hipersensibilidade cut\u00e2nea ao soro.<\/span><\/li>\n<\/ol>\n

    [\/et_pb_text][et_pb_text admin_label=”Cutaneous” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ header_font=”Montserrat||||||||” header_text_align=”left” header_2_font=”Montserrat||||||||” header_2_font_size=”35px” header_2_line_height=”1.3em” header_3_font=”Montserrat||||||||” header_3_line_height=”1.4em” background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 5%|#ffffff 100%” custom_margin=”|||0px|false|false” custom_padding=”10px||10px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Teste de hipersensibilidade cut\u00e2nea:<\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”Antivenom” _builder_version=”4.17.4″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ background_color_gradient_direction=”108deg” background_color_gradient_start_position=”4%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    O antiveneno deve ser dilu\u00eddo 1:10 com solu\u00e7\u00e3o salina est\u00e9ril (uma dilui\u00e7\u00e3o 1:100 deve ser considerada quando o hist\u00f3rico do paciente sugerir alergia a prote\u00ednas equinas). Em seguida, 0,1 mL do antiveneno dilu\u00eddo \u00e9 injetado por via intrad\u00e9rmica na superf\u00edcie externa do bra\u00e7o, de modo que se forme uma pequena ves\u00edcula. Uma rea\u00e7\u00e3o positiva, evidenciando alergia, manifesta-se pelo aparecimento de vermelhid\u00e3o e coceira no local da inje\u00e7\u00e3o em 20 minutos. Pacientes com sensibilidade muito alta podem apresentar manifesta\u00e7\u00f5es al\u00e9rgicas sist\u00eamicas, como broncoespasmo, urtic\u00e1ria generalizada ou hipotens\u00e3o. \u00c9 necess\u00e1rio manter a adrenalina (1:1000) para tratar rea\u00e7\u00f5es adversas t\u00e3o fortes. Em caso de teste cut\u00e2neo positivo, o soro n\u00e3o pode ser administrado em campo devido ao risco de choque anafil\u00e1tico, devendo o paciente ser transportado ao hospital ou posto de sa\u00fade mais pr\u00f3ximo para receber o soro. Se o teste cut\u00e2neo for negativo, o antiveneno pode ser administrado. No entanto, existem alguns casos que apresentam rea\u00e7\u00f5es anafil\u00e1ticas \u00e0 administra\u00e7\u00e3o sist\u00eamica de soro antiof\u00eddico mesmo com teste cut\u00e2neo negativo.<\/span><\/p>\n

    [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_image src=”https:\/\/www.echitabplusicp.org\/wp-content\/uploads\/2022\/03\/P1010063.png” title_text=”P1010063″ align=”center” force_fullwidth=”on” _builder_version=”4.16″ _module_preset=”default” border_radii=”off|30px|30px|30px|30px” box_shadow_style=”preset4″ global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_image][et_pb_text _builder_version=”4.16″ _module_preset=”b09d8a78-dea9-4496-9ad6-48ab48739ffd” header_font=”Times New Roman||||||||” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Antiveneno poliespec\u00edfico contra Echis Ocellatus, Bitis Arietans e Naja Nigricollis<\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”Administration” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ header_font=”Montserrat||||||||” header_text_color=”#3D3D3D” header_2_font=”Montserrat||||||||” header_2_font_size=”35px” header_2_line_height=”1.3em” header_3_font=”Montserrat||||||||” header_3_line_height=”1.4em” background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 5%|#ffffff 100%” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Administra\u00e7\u00e3o de soro antiof\u00eddico em condi\u00e7\u00f5es de campo:<\/span><\/span><\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”Keep in mind” _builder_version=”4.17.4″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ custom_margin=”|||0px|false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Lembre-se de que o soro antiof\u00eddico pode ser administrado em campo somente quando o teste cut\u00e2neo for negativo. Em condi\u00e7\u00f5es de campo, o antiveneno deve ser administrado apenas por via intramuscular, desinfec\u00e7\u00e3o pr\u00e9via da pele com etanol. A dose do antiveneno a ser administrada por via intramuscular corresponde a quatro frascos, que devem ser injetados em at\u00e9 15 minutos. Independentemente de o paciente ter ou n\u00e3o recebido soro antiof\u00eddico em campo, ele precisa ser transportado ao posto de sa\u00fade mais pr\u00f3ximo para avalia\u00e7\u00e3o cl\u00ednica e acompanhamento.<\/span><\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”Administration_of” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ header_font=”Montserrat||||||||” header_2_font=”Montserrat||||||||” header_2_font_size=”35px” header_2_line_height=”1.3em” header_3_font=”Montserrat||||||||” header_3_line_height=”1.4em” background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 6%|#ffffff 100%” custom_padding=”10px||8px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Administra\u00e7\u00e3o de antiveneno em centros de sa\u00fade
    (somente para profissionais de sa\u00fade):<\/span><\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”In Health” _builder_version=”4.17.4″ _module_preset=”c30b9b6a-508c-466b-9581-d6d9761688b4″ custom_margin=”|||0px|false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Nos centros de sa\u00fade, o antiveneno deve ser administrado por via intravenosa apenas pela equipe de sa\u00fade. Uma avalia\u00e7\u00e3o cl\u00ednica deve ser realizada para determinar se o paciente apresenta sinais e sintomas de envenenamento. Envenenamentos por esp\u00e9cies de viper\u00eddeos (Echis sp.,<\/span>Bitis sp.)<\/span> s\u00e3o caracterizadas por efeitos locais (edema, dor, sangramento local e necrose em casos graves) e\/ou por sangramento sist\u00eamico e dist\u00farbios de coagula\u00e7\u00e3o. Envenenamentos por esp\u00e9cies de cobras citot\u00f3xicas (<\/span>Naja nigricollis)<\/span> caracterizam-se por necrose local, sem sangramento sist\u00eamico e sem dist\u00farbios de coagula\u00e7\u00e3o. Em caso de envenenamento, deve ser administrada uma dose de quatro frascos de soro antiof\u00eddico.<\/span><\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”Protocol” _builder_version=”4.17.4″ _module_preset=”b70b3a13-c826-4509-b565-60d0eb25eb09″ header_font=”Montserrat||||||||” header_2_font=”Montserrat||||||||” header_2_font_size=”35px” header_2_line_height=”1.3em” header_3_font=”Montserrat||||||||” header_3_line_height=”1.4em” background_color_gradient_direction=”108deg” background_color_gradient_stops=”#f5f5f5 5%|#ffffff 100%” custom_padding=”10px||8px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

    Protocolo para administra\u00e7\u00e3o de antiveneno
    nos centros de sa\u00fade:<\/span><\/p>\n

    [\/et_pb_text][et_pb_text admin_label=”List” _builder_version=”4.16″ _module_preset=”2d83f41d-a2fc-49a5-9e22-591a14d0651c” custom_margin=”|||0px|false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n

      \n
    1. Canular atrav\u00e9s de um I.V. rota.<\/span><\/li>\n
    2. Diluir a dose do soro antiof\u00eddico a ser utilizado com 500 mL de soro fisiol\u00f3gico (200 mL no caso de crian\u00e7as, para evitar sobrecarga h\u00eddrica). Iniciar a infus\u00e3o do soro antiof\u00eddico em fluxo baixo. Manter uma observa\u00e7\u00e3o atenta do paciente por 20 minutos para detectar poss\u00edveis rea\u00e7\u00f5es adversas precoces \u00e0 administra\u00e7\u00e3o do antiveneno.<\/span><\/li>\n
    3. Caso n\u00e3o haja evid\u00eancia de rea\u00e7\u00f5es adversas precoces, aumentar o fluxo de administra\u00e7\u00e3o do antiveneno de forma que toda a dose seja administrada em 1 hora.<\/span><\/li>\n
    4. Se houver rea\u00e7\u00f5es adversas precoces (urtic\u00e1ria, hipotens\u00e3o, broncoespasmo), interromper imediatamente a infus\u00e3o do soro antiof\u00eddico e administrar anti-histam\u00ednicos e corticoster\u00f3ides por via intravenosa; no caso de rea\u00e7\u00f5es graves, a adrenalina 1:1000 deve ser administrada por via subcut\u00e2nea. Uma vez controladas as manifesta\u00e7\u00f5es da rea\u00e7\u00e3o adversa, reiniciar a infus\u00e3o do soro antiof\u00eddico, conforme descrito no item (b).<\/span><\/li>\n
    5. As manifesta\u00e7\u00f5es hemorr\u00e1gicas e os dist\u00farbios de coagula\u00e7\u00e3o devem ser controlados dentro de 12 horas ap\u00f3s a administra\u00e7\u00e3o do antiveneno, desde que uma dose adequada tenha sido administrada. Se o sangramento local ou sist\u00eamico persistir, ou se as altera\u00e7\u00f5es de coagula\u00e7\u00e3o n\u00e3o tiverem sido revertidas at\u00e9 esse momento, uma dose adicional de 4 frascos de soro antiof\u00eddico deve ser administrada, dependendo da gravidade do envenenamento, conforme indicado acima. H\u00e1 casos em que ocorre recorr\u00eancia do envenenamento, ou seja, as manifesta\u00e7\u00f5es cl\u00ednicas do envenenamento reaparecem ap\u00f3s seu controle inicial. Isso se deve ao atraso na absor\u00e7\u00e3o do veneno dos dep\u00f3sitos nos tecidos e requer uma administra\u00e7\u00e3o adicional de 4 frascos de soro antiof\u00eddico.<\/span><\/li>\n
    6. A terapia do envenenamento of\u00eddico inclui, al\u00e9m da administra\u00e7\u00e3o do antiveneno, uma s\u00e9rie de interven\u00e7\u00f5es auxiliares como: administra\u00e7\u00e3o de profilaxia do t\u00e9tano, administra\u00e7\u00e3o de antibi\u00f3ticos e outras interven\u00e7\u00f5es que dependem das caracter\u00edsticas cl\u00ednicas de cada caso.<\/span><\/li>\n
    7. Rea\u00e7\u00f5es adversas tardias \u00e0 terapia com soro antiof\u00eddico: A administra\u00e7\u00e3o de soro antiof\u00eddico polivalente pode resultar em doen\u00e7a do soro dentro de 5 a 20 dias em uma pequena porcentagem de pacientes. As manifesta\u00e7\u00f5es cl\u00ednicas da doen\u00e7a do soro incluem febre, urtic\u00e1ria, artralgias e linfadenopatia. Essas rea\u00e7\u00f5es s\u00e3o tratadas com anti-histam\u00ednicos e corticoster\u00f3ides.<\/span><\/li>\n<\/ol>\n

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      EchiTAb-Plus-ICPINSTITUTOCLODOMIRO PICADOUniverdad da Costa RicaEchiTAb-Plus-ICPL\u00cdQUIDO ANTIVEN\u00cdFICO POLISPEC\u00cdFICO(Anti-v\u00edboras, anti-elaps)Descri\u00e7\u00e3o e instru\u00e7\u00f5esPot\u00eanciaCadafrasco de 10 mL neutraliza pelo menos 30 mg. de veneno de E. ocellatus, 20 mg de B. arietans e 2 mg de veneno de N. nigricollis.Excipientes q.s. 10ml.Composi\u00e7\u00e3oImunoglobulinas equinas q.s. de modo que cada mililitro neutralize pelo menos 3,0 mg de veneno de Echis ocellatus, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-245667","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/pages\/245667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/comments?post=245667"}],"version-history":[{"count":8,"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/pages\/245667\/revisions"}],"predecessor-version":[{"id":245685,"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/pages\/245667\/revisions\/245685"}],"wp:attachment":[{"href":"https:\/\/www.echitabplusicp.org\/pt-pt\/wp-json\/wp\/v2\/media?parent=245667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}